Genomics allows individualize treatments for cancer patients, explains Dr. Howard Lim, medical oncologist, BC Cancer.

Breaking down cancer with genomics

Donor funding has played a pivotal role in advancing genomics research

“It was like a miracle.”

Trish Keating was diagnosed with colon cancer in 2010 and after surgery, chemotherapy and radiation treatment, she was told in 2013 when her cancer returned that it was terminal.

After enrolling in the Personalized Onco-Genomics (POG) Program at BC Cancer, the team of experts discovered Trish’s cancer was driven by a specific protein. They then identified and administered an existing blood pressure medication that is known to block pathways to that protein.

The results were rapid and dramatic: eight weeks after starting her new treatment, Trish was tumour-free.

“It’s still so hard to believe,” says Trish. “I was months away from death.”

Trish’s experience is just one example of how genomics – where experts deploy whole genome analysis to inform individual treatment planning for patients – is transforming cancer care for people across B.C.

“The use of genomics is trying to understand the blueprint – what we call the genome – to a cancer, and by understanding that blueprint we can then start to individualize treatments for patients,” says Dr. Howard Lim, medical oncologist, BC Cancer. “Genomics will change not only how we treat cancer, but also how we detect and prevent cancer.”

Cancer genomes are as unique as a fingerprint, and no two genomes are identical. Therefore, says Dr. Lim, cancer treatment can no longer be one-size-fits-all.

“We’re beginning to understand that not all cancers are the same and certain ones respond differently to different treatments, or don’t respond at all to particular treatments,” he says. “With this knowledge we can begin to tailor the type of chemotherapy or targeted agents that we can use for treating specific cancers.”

Dr. Lim says donor funding has played a pivotal role in advancing genomics research, which is also the fundraising focus of BC Cancer Foundation’s Inspiration Gala on Nov. 2.

“The basic science we do to help further all of this research is thanks to donor support – it makes a huge impact to all of us in the clinic,” says Dr. Lim. “In fact, a lot of the research and treatments we’ve moved forward with is because of BC Cancer Foundation donors.”

You can help transform the standard of cancer care with genomically informed treatments for British Columbians facing cancer. Learn more at www.bccancerfoundation.com.

Comments are closed

Just Posted

Surrey school district to allow students to miss class for global climate strike

Students must be excused from school by parents; will be able to make up missed work without penalty

Surrey rallies for change in global climate strike

Holland Park event part of marches around the world Sept. 20

Surrey RCMP need help to find missing man

Denis Godard, 64, who was reported missing on Sept. 19

Little library stolen in Clayton Heights

Thieves permanently check out family’s book collection

Surrey council sends back 25-storey highrise proposal, asks for more height and density

Developer says it is ‘currently reviewing direction’ from mayor, council

Handgun crackdown, health spending and transit plans latest campaign promises

Friday was the end of a busy week on the campaign trail

One-in-five British Columbians think they’ll win big while gambling: study

Roughly 58 per cent of British Columbians bought at least one lottery ticket in past year

Takaya, B.C.’s infamous lone wolf, seen eating seal and howling away on Discovery Island

Fun facts about Takaya the wolf, like his a 36-hour tour around Chatham, Discovery Islands

Resident finds loaded shotgun inside a duffle bag in Kelowna alleyway

RCMP seized a loaded 12-gauge shotgun, ammunition, clothing and other items

Graffiti, calls and Snapchat: RCMP probe string of threats targeting Kamloops schools

There have been nine different threats made to four different schools in the city

Oak Bay father’s testimony at murder trial like plot of ‘bad low-budget movie:’ Crown

Crown alleged Andrew Berry’s ‘entire story of Christmas Day is a lie’

B.C. truck drivers to face higher fines for not using winter tire chains

As of Oct. 1, not using chains on the highway when required could net you a $598 ticket

Singh campaigns in Toronto, May in Winnipeg, as Liberal and Tory leaders pause

All parties expected to be back on the campaign trail Sunday

Most Read