Simon Fraser University announced on March 3, 2020 that researchers in its Brinkman Laboratory have collaborated with U.S. researchers to analyze a new drug that can kill a wide range of superbugs. (Simon Fraser University photo)

Human trials underway after B.C. researchers analyze effects of new ‘superbug-killing compound’

Brinkman Lab in Burnaby helped analyze effects of new drug after University of Cincinnati discovery

Researchers at Simon Fraser University’s Brinkman Lab in Burnaby participated in a landmark study that tests how a new drug can kill a range of superbugs – including some bacteria now resistant to all common antibiotics.

According to a March 3 release, researchers at the University of Cincinnati discovered two inexpensive chemicals work to kill disease-causing bacteria more effectively when combined.

The U.S. researchers combined the chemicals — ethylenediaminetetraacetic acid and acidified nitrite — to create the new drug known as AB569.

ALSO READ: B.C. widow sues health authority after ‘untreatable’ superbug killed husband

SFU researchers then used computers to analyze data from bacteria treated with the new drug. The results from the study indicated the drug can kill pathogens identified by the World Health Organization as urgently requiring new treatments, and posing the greatest threat to human health.

For example, the top three “priority pathogens” include Pseudomonas aeruginosa, a type of bacteria that can cause infections in the lungs, urinary tract, or blood that is known as the leading cause of morbidity in patients with cystic fibrosis.

Erin Gill, a PhD researcher at the University of British Columbia during the study and now at the Brinkman Lab, was involved in the analysis. She told Black Press Media by phone that it was inspiring to be part of “such a large, collaborative project.”

“It’s really important work to be able to contribute to the discovery of potentially novel drugs that can help to kill bacteria, because we’re running out of them,” Gill said.

The lab’s lead database developer Geoff Winsor agreed.

“We have a growing crisis with antibiotics becoming less and less effective, and treatments are failing,” Winsor said. “That’s why it’s important to test and develop new drugs and approaches to treat disease-causing bacteria that are highly resistant to existing antibiotics.”

The new drug is currently in the first phase of human trials that are being managed by Toronto-based biotechnology firm Arch Biopartners.

“I think they’re going to have some results from that soon,” Winsor said.

ALSO READ: SFU reviewing security measures after data breach exposes personal information

Correction: This story has been updated. The University of Cincinnati was responsible for testing the new AB569 drug, not the SFU Brinkman Lab.



karissa.gall@blackpress.ca

Like us on Facebook and follow us on Twitter

SFU

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Thousands of ‘PPE’ donated in Surrey, where one care home is ‘preparing for the worst’

SafeCare BC’s Operation Protect drive involves drop-off dates in Guildford

Psychologist’s advice on parenting in the pandemic

SFU psychology prof Dr. Tanya Broesch, with expertise in child development, discusses short and long-term impacts COVID-19 pandemic is having on children and parents alike

‘Every little step counts’: Surrey businesses donate meals for frontline hospital workers

Surrey Hospital Foundation has now received more than $70,000 in donations

‘Shocking decision’: Surrey soccer club won’t offer refunds to 350 teams for cancelled tourney

Registration fees would top $171K for Surrey Mayor’s Cup, called off due to COVID-19

VIDEO: Dog missing in Aldergrove since winter sees his family again for the first time

Aldergrove helped find Buster, says dad, who has now witnessed ‘the power of social media’

Trudeau rejects mandatory stay-at-home order for now; COVID deaths up

The virus has now infected more than 10,000 Canadians and cost 130 their lives

B.C. health care workers gain access to virtual health care options

During COVID-19 many clinics have closed, leaving health care workers with nowhere to turn

Tax collectors, auditors to help field ‘historic’ numbers of benefit-seeking callers

‘If you work for CRA, people think we are just there to take money from your pockets.’

Cowichan couple won’t self-isolate after returning from overseas

New law requires 14 days of self-isolation when returning to Canada

Family uses social media to help truckers find places to eat during pandemic

Restaurants Serving Drivers in Western Canada seeks to provide a list of places open for drivers

Advocates sound alarm over COVID-19 limiting access to contraceptives, abortion

The COVID-19 outbreak has hit sexual-health services from almost every angle

Abbotsford man who tries to start gas-station fight gets sprayed with gasoline

Suspect returns with knife and throws it at victim, but is quickly arrested by police

Abbotsford family of 5 who was stuck in Vietnam is now back home

Janzen family sends ‘huge and heartfelt’ thank you to everyone who helped

Most Read